Monroe is 3-1 coming off a three game winning streak, Franklin-Simpson is 2-2 after losing last week to Greenwood. The only teams that both have seen this year is Greenwood, and Monroe handled them very good 35-0 in a scrimmage. I know this may not be the same Greenwood that played last week but that's there only comparable schools.
IMHO I think Monroe handles FS Friday. Monroe by 17