On October 29, 1921, Centre College beat Harvard 6-0. At the time, Harvard was a football powerhouse and had won 25 straight games. The Associated Press in 1950 considered this the biggest upset in college football in the half century. Centre's Bo McMillin, who played high school ball at Somerset High School, scored on a 32 yard touchdown run in the third quarter to become the hero for that day. McMillin went on to lead Centre to a formidable 25-2 record leading into this game. He became Coach and General Manager for the Detroit Lions in the NFL. Then became coach at Indiana University.