Depends on where you are in the season. In the early weeks you want as many kids getting playing time as possible. Have to see what your backups can do with the #1's. Have to see where some of your own weaknesses are so you can improve on them. Have to see if somethings you may or may not use later will work.
The district part of the schedule gets tricky, still need to work on things, but also dont want any injuries, so you balance it.
Last 2 weeks of the regular season, you get there as fast as possible and go home.
I also think your roster size plays a part in this, the bigger the roster, the more players to get playing time for, the less running clocks you may want.
Also, when you play your JV games has a factor in this too. Many NKY teams play JV on Saturday mornings, you dont want to play your JV guys too long on Friday night, then play them again less than 12 hours later.