I think Knott's experience will help them alot but also, Calloway hasnt faced this kind of talent. People dog Knott for a weak schedule but has anyone looked at Calloway's? Knott has a few top 20 teams on their schedule. Im not sure Calloway has played a top 50 team.
As long as Knott can make some shots, they'll be ok. If not, Calloway may be able to hang around.
Every game that Knott has lost in the sweet 16 they have shot 32% or less. In the games they've won, they have shot 40% or better.
I think Knott is capable of winning this game by 15-20 points if they make some shots. If they come out cold, it may just be a few points.