Obviously, I would have scouted the team so thoroughly, I'd probably know what every player eats for breakfast :-)
That said, my gameplan (because I like to play straight up man-to-man) would be to work on getting the ball out of the "primary ball handler"'s hands (whoever that may be in game 1) and not letting them get it back. This would help in the regional game when the gameplan would clearly be: Make somebody other than the PG beat you. Then I would use a quicker player to front the post and exaggerate weak side help on the post player to help deny him touches. If a team has two dominant players, the gameplan is to make the other 13 guys on the roster do something they may or may not be able to do.
I've never liked the idea of pressing a team with a really good point guard for 1 reason: Most "really good" point guards find open players and don't get flustered when facing a trap; this allows the other team to slice and dice your press. Play straight up and try to make others beat you.
On offense, I'd put a lineup on the floor requiring the post player to play on-ball perimeter defense on my wings. Who knows? Maybe he'll get in foul trouble early and open up the paint some more.